Functioning of Traditional Bottles
Once you squeeze the bottle, the drug comes out of the bottle, and upon releasing the squeeze, the ambient non-sterile air & the left over drop exposed to ambient environment renters the bottle from the same path as that of the drug, the it will carry the contaminants of environment inside the bottle.These ambient contaminants can cause microbial growth and load on drug bioburden.
Need for Preservatives
To lower the effect & negate the microbial load, preservatives are added into the drugs product to prevent the growth of microbial contaminants in the product and maintain sterility for certain time period. Thus, preservatives have become a key component in ophthalmic formulations to achieve a stable product shelf life if needs to be used multiple times. Some of the common preservatives used are:
Benzalkonium chloride (BAC/BAK), Stabilized Oxychloro Complex (SOC) SofZia
These Preservatives acts as evils in the conventional eye dropper bottles, various studies have proved that
Chronic exposure to preservatives has been associated with some side effects, mainly toxicity and adverse changes to the ocular surface resulting in disease advancement
How can we improve Patient Adherence?
Choose an easy to use, convenient and ergonomic system
Take a sustainable and affordable long-term medicine
Reduce side effects such as eye irritations, by eliminating preservatives
Take accurate dosage with better precision
Avoid irritations, allergies and other side effects, Introducing MDPF (Multi-Dose Preservative free) Technology by Eyekare Kilitch
0% Preservatives, 100% Eye Protection
Eyekare Kilitch uses Novelia bottles manufactured by Nemera,
France which has multidose caping system with patented Pureflow technology.
Doctors Recommended Brand
87% of Doctors interviewed preferred MDPF Novela Technology for long-term therapy
76% of Doctors think that MDPF would enhance compliance to their current treatment
System Benefits
‘Novelia ®’, a technology from France, brought in India for the first time by Eyekare Kilitch Ltd., is the solution that provides the benefit of the medication without the ill effects of any preservatives.
The state of art technology prevents bacterial contamination and avoids the need of preservatives over treatment duration Benefits of Preservative-free multi dose formulations are as under technology from France, brought in India for the first time by Eyekare Kilitch Ltd., is the solution that provides the benefit of the medication without the ill effects of any preservatives.
The state of art technology prevents bacterial contamination and avoids the need of preservatives over treatment duration Benefits of Preservative-free multi dose formulations are as under
System Benefits:
‘Novelia ®’, a technology from France, brought in India for the first time by Eyekare Kilitch Ltd., is the solution that provides the benefit of the medication without the ill effects of any preservatives.
The state of art technology prevents bacterial contamination and avoids the need of preservatives over treatment duration Benefits of Preservative-free multi dose formulations are as under
Principle of the MDPF System
On squeezing the liquid flows out of the bottle through a defined path dispensing uniform dosage. (→)
Contaminated air ( → ) or contaminated liquid from atmosphere cannot flow back into the bottle due to the presence of Non return valve in the nozzle. (→)
Air compensation happens by entry of ambient air or liquid from ambient atmosphere through the aperture provided on the side of the bottle, through the homogenous silicon membrane which allows only gases to flow through, arresting the microbes. (→)
Permeability Pure Flow Technology
Air compensation happens by entry of ambient air or liquid from ambient atmosphere through the aperture provided on the side of the bottle, through the homogenous silicon membrane which allows only gases to flow through, arresting the microbes.
Controlled & Safe
Each Assembled product is controlled and manufactured on a Robotic line non-return valve works well to ensure no liquid back-flow into the system silicone membrane is tight and acts as a barrier against contaminated air.
Functioning of MDPF system in Nutshell
Each Assembled product is controlled and manufactured on a Robotic line non-return valve works well to ensure no liquid back-flow into the system silicone membrane is tight and acts as a barrier against contaminated air.
Bottle Squeezing
Bottle Squeezing
Valve opening
Valve Opening
Valve reclosing
Valve Reclosing
Air compensation
Air Compensation
MDPF System Specifications
Cap
- Made of durable, lightweight HDPE with antimicrobial silver agents in the cap; no drug contact.
Nozzle Bottom
- Made of lightweight, durable HDPE with antimicrobial silver agents in the cap; no drug contact.
Top
Spring
- Material of construction : Silicone Rubber
- contact with Drug: No
Nozzle Venting System
- Homogeneous silicone membrane prevents contaminated air entry; drug contact: yes.
Top
Non-return Valve
- Made of lightweight, durable HDPE with antimicrobial silver agents in the cap; no contact with the drug.
Bottle
- Material of construction: Low density poly ethylene
- contact with drug – yes
MDPF System Specifications
Cap
- Made of HDPE (High density poly ethylene) material – It’s lightweight yet super-strong
- Silver agents (anti-microbial) are used in the CAP
- Contact with drug – No
Top
- Made of HDPE (High density poly ethylene) material – It’s lightweight yet super-strong
- With Silver ions for anti-microbial activity
- Contact with Drug: No
Spring
- Material of construction : Silicone Rubber
- contact with Drug: No
Non-return Valve
- Avoids back flow so no contaminated/ambient air or liquid can enter the bottle
- Material of Construction: Silicon Rubber
- Blue colorant
- Contact with Drug: Yes
Nozzle Bottom
- Material of construcon: HDPE
- Contact with Drug: Yes
Nozzle Venting System
- It’s a homogeneous and continue Silicone membrane
- No contaminated air can enter into bottle
- contact with drug – yes
Bottle
- Avoids back flow so no contaminated/ambient air or liquid can enter the bottle
- Material of Construction: Silicon Rubber
- Blue colorant
- Contact with Drug: Yes
MDPF System Specifications
Cap
- Made of HDPE (High density poly ethylene) material – It’s lightweight yet super-strong
- Silver agents (anti-microbial) are used in the CAP
- Contact with drug – No
Top
- Made of HDPE (High density poly ethylene) material – It’s lightweight yet super-strong
- With Silver ions for anti-microbial activity
- Contact with Drug: No
Spring
- Material of construction : Silicone Rubber
- contact with Drug: No
Non-return Valve
- Avoids back flow so no contaminated/ambient air or liquid can enter the bottle
- Material of Construction: Silicon Rubber
- Blue colorant
- Contact with Drug: Yes
Nozzle Bottom
- Material of construcon: HDPE
- Contact with Drug: Yes
Nozzle Venting System
- It’s a homogeneous and continue Silicone membrane
- No contaminated air can enter into bottle
- contact with drug – yes
Bottle
- Avoids back flow so no contaminated/ambient air or liquid can enter the bottle
- Material of Construction: Silicon Rubber
- Blue colorant
- Contact with Drug: Yes
Products in MDPF Technology
Manufacturing Excellence
All the products are manufactured by the groups manufacturing division Kilitch Healthcare having state of the art manufacturing facility compliant to all the major international regulatory requirements. Kilitch Healthcare holds all the intellectual formulation rights whereby the groups research team develops the drug formulations. These are then filled in technologically engineered Noveila bottles, a French innovation designed and manufactured by Nemera, France. Kilitch Healthcare manufactures products under its own banner of Eyekare and open for Third Party manufacturing.
Frequently Asked Questions
Find answers to common questions about preservative-free eye drops, including their benefits, usage, storage, and potential side effects.
Preservative-free eye drops are formulations that do not contain preservatives, which are chemicals added to prevent bacterial contamination. These drops are often recommended for individuals with sensitive eyes or those who experience irritation from preservatives.
Preservative-free eye drops are beneficial for people with chronic eye conditions like glaucoma, as they reduce the risk of ocular surface disease and irritation. They are especially useful for patients who need to use multiple eye drops daily.
The most frequently used preservative in eye drops is Benzalkonium Chloride (BAK), which is effective against microorganisms but can cause inflammation and cell disruption. Other preservatives like Purite and SofZia are less disruptive and better tolerated by some patients.
To use preservative-free eye drops, wash your hands thoroughly, tilt your head back, and pull down your lower eyelid to create a small pocket. Squeeze one drop into the pocket without touching the dropper to your eye or eyelid. Close your eye for a few moments to allow the drop to spread evenly.
GET IN TOUCH WITH US
GET IN TOUCH WITH US
Locate Us On Map
Have Any Thing To Ask ? We Always Ready
Corporate Office
EYEKARE KILITCH LIMITED
902-B, Godrej Coliseum, Behind Everard Nagar, Off. Eastern Express Highway, Nr. Priyadarshani Circle, Sion (E.), Mumbai – 400 022. INDIA.
+91-22-6137 2222
9:30 - 5:30 Mon - Fri
info@ekl.kilitchhealthcare.com
Subscribe Our News Letter!
Functioning of Traditional Bottles
Once you squeeze the bottle, the drug comes out of the bottle, and upon releasing the squeeze, the ambient non-sterile air & the left over drop exposed to ambient environment renters the bottle from the same path as that of the drug, the it will carry the contaminants of environment inside the bottle.These ambient contaminants can cause microbial growth and load on drug bioburden.
Need for Preservatives
To lower the effect & negate the microbial load, preservatives are added into the drugs product to prevent the growth of microbial contaminants in the product and maintain sterility for certain time period. Thus, preservatives have become a key component in ophthalmic formulations to achieve a stable product shelf life if needs to be used multiple times. Some of the common preservatives used are:
Benzalkonium chloride (BAC/BAK), Stabilized Oxychloro Complex (SOC) SofZia
These Preservatives acts as evils in the conventional eye dropper bottles, various studies have proved that
Chronic exposure to preservatives has been associated with some side effects, mainly toxicity and adverse changes to the ocular surface resulting in disease advancement
How can we improve Patient Adherence?
Choose an easy to use, convenient and ergonomic system
Take a sustainable and affordable long-term medicine
Reduce side effects such as eye irritations, by eliminating preservatives
Take accurate dosage with better precision
Avoid irritations, allergies and other side effects, Introducing MDPF (Multi-Dose Preservative free) Technology by Eyekare Kilitch
0% Preservatives, 100% Eye Protection
Eyekare Kilitch uses Novelia bottles manufactured by Nemera,
France which has multidose caping system with patented Pureflow technology.
Doctors Recommended Brand
87% of Doctors interviewed preferred MDPF Novela Technology for long-term therapy
76% of Doctors think that MDPF would enhance compliance to their current treatment
System Benefits
‘Novelia ®’, a technology from France, brought in India for the first time by Eyekare Kilitch Ltd., is the solution that provides the benefit of the medication without the ill effects of any preservatives.
The state of art technology prevents bacterial contamination and avoids the need of preservatives over treatment duration Benefits of Preservative-free multi dose formulations are as under technology from France, brought in India for the first time by Eyekare Kilitch Ltd., is the solution that provides the benefit of the medication without the ill effects of any preservatives.
The state of art technology prevents bacterial contamination and avoids the need of preservatives over treatment duration Benefits of Preservative-free multi dose formulations are as under
System Benefits:
‘Novelia ®’, a technology from France, brought in India for the first time by Eyekare Kilitch Ltd., is the solution that provides the benefit of the medication without the ill effects of any preservatives.
The state of art technology prevents bacterial contamination and avoids the need of preservatives over treatment duration Benefits of Preservative-free multi dose formulations are as under
Principle of the MDPF System
On squeezing the liquid flows out of the bottle through a defined path dispensing uniform dosage. (→)
Contaminated air ( → ) or contaminated liquid from atmosphere cannot flow back into the bottle due to the presence of Non return valve in the nozzle. (→)
Air compensation happens by entry of ambient air or liquid from ambient atmosphere through the aperture provided on the side of the bottle, through the homogenous silicon membrane which allows only gases to flow through, arresting the microbes. (→)
Permeability Pure Flow Technology
Air compensation happens by entry of ambient air or liquid from ambient atmosphere through the aperture provided on the side of the bottle, through the homogenous silicon membrane which allows only gases to flow through, arresting the microbes.
Controlled & Safe
Each Assembled product is controlled and manufactured on a Robotic line non-return valve works well to ensure no liquid back-flow into the system silicone membrane is tight and acts as a barrier against contaminated air.
Functioning of MDPF system in Nutshell
Each Assembled product is controlled and manufactured on a Robotic line non-return valve works well to ensure no liquid back-flow into the system silicone membrane is tight and acts as a barrier against contaminated air.
Bottle Squeezing
Bottle Squeezing
Valve opening
Valve Opening
Valve reclosing
Valve Reclosing
Air compensation
Air Compensation
MDPF System Specifications
Cap
- Made of durable, lightweight HDPE with antimicrobial silver agents in the cap; no drug contact.
Nozzle Bottom
- Made of lightweight, durable HDPE with antimicrobial silver agents in the cap; no drug contact.
Top
Spring
- Material of construction : Silicone Rubber
- contact with Drug: No
Nozzle Venting System
- Homogeneous silicone membrane prevents contaminated air entry; drug contact: yes.
Top
Non-return Valve
- Made of lightweight, durable HDPE with antimicrobial silver agents in the cap; no contact with the drug.
Bottle
- Material of construction: Low density poly ethylene
- contact with drug – yes
MDPF System Specifications
Cap
- Made of HDPE (High density poly ethylene) material – It’s lightweight yet super-strong
- Silver agents (anti-microbial) are used in the CAP
- Contact with drug – No
Top
- Made of HDPE (High density poly ethylene) material – It’s lightweight yet super-strong
- With Silver ions for anti-microbial activity
- Contact with Drug: No
Spring
- Material of construction : Silicone Rubber
- contact with Drug: No
Non-return Valve
- Avoids back flow so no contaminated/ambient air or liquid can enter the bottle
- Material of Construction: Silicon Rubber
- Blue colorant
- Contact with Drug: Yes
Nozzle Bottom
- Material of construcon: HDPE
- Contact with Drug: Yes
Nozzle Venting System
- It’s a homogeneous and continue Silicone membrane
- No contaminated air can enter into bottle
- contact with drug – yes
Bottle
- Avoids back flow so no contaminated/ambient air or liquid can enter the bottle
- Material of Construction: Silicon Rubber
- Blue colorant
- Contact with Drug: Yes
MDPF System Specifications
Cap
- Made of HDPE (High density poly ethylene) material – It’s lightweight yet super-strong
- Silver agents (anti-microbial) are used in the CAP
- Contact with drug – No
Top
- Made of HDPE (High density poly ethylene) material – It’s lightweight yet super-strong
- With Silver ions for anti-microbial activity
- Contact with Drug: No
Spring
- Material of construction : Silicone Rubber
- contact with Drug: No
Non-return Valve
- Avoids back flow so no contaminated/ambient air or liquid can enter the bottle
- Material of Construction: Silicon Rubber
- Blue colorant
- Contact with Drug: Yes
Nozzle Bottom
- Material of construcon: HDPE
- Contact with Drug: Yes
Nozzle Venting System
- It’s a homogeneous and continue Silicone membrane
- No contaminated air can enter into bottle
- contact with drug – yes
Bottle
- Avoids back flow so no contaminated/ambient air or liquid can enter the bottle
- Material of Construction: Silicon Rubber
- Blue colorant
- Contact with Drug: Yes
Products in MDPF Technology
Manufacturing Excellence
All the products are manufactured by the groups manufacturing division Kilitch Healthcare having state of the art manufacturing facility compliant to all the major international regulatory requirements. Kilitch Healthcare holds all the intellectual formulation rights whereby the groups research team develops the drug formulations. These are then filled in technologically engineered Noveila bottles, a French innovation designed and manufactured by Nemera, France. Kilitch Healthcare manufactures products under its own banner of Eyekare and open for Third Party manufacturing.
Frequently Asked Questions
Find answers to common questions about preservative-free eye drops, including their benefits, usage, storage, and potential side effects.
Preservative-free eye drops are formulations that do not contain preservatives, which are chemicals added to prevent bacterial contamination. These drops are often recommended for individuals with sensitive eyes or those who experience irritation from preservatives.
Preservative-free eye drops are beneficial for people with chronic eye conditions like glaucoma, as they reduce the risk of ocular surface disease and irritation. They are especially useful for patients who need to use multiple eye drops daily.
The most frequently used preservative in eye drops is Benzalkonium Chloride (BAK), which is effective against microorganisms but can cause inflammation and cell disruption. Other preservatives like Purite and SofZia are less disruptive and better tolerated by some patients.
To use preservative-free eye drops, wash your hands thoroughly, tilt your head back, and pull down your lower eyelid to create a small pocket. Squeeze one drop into the pocket without touching the dropper to your eye or eyelid. Close your eye for a few moments to allow the drop to spread evenly.
GET IN TOUCH WITH US
GET IN TOUCH WITH US
Locate Us On Map
Have Any Thing To Ask ? We Always Ready
Corporate Office
EYEKARE KILITCH LIMITED
902-B, Godrej Coliseum, Behind Everard Nagar, Off. Eastern Express Highway, Nr. Priyadarshani Circle, Sion (E.), Mumbai – 400 022. INDIA.
+91-22-6137 2222
9:30 - 5:30 Mon - Fri
info@ekl.kilitchhealthcare.com
Subscribe Our News Letter!
Have Any Thing To Ask ? We Always Ready
Corporate Office
EYEKARE KILITCH LIMITED
902-B, Godrej Coliseum, Behind Everard Nagar, Off. Eastern Express Highway, Nr. Priyadarshani Circle, Sion (E.), Mumbai – 400 022. INDIA.